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Molecular Radiopharmacy: PDF Print E-mail

Research and development of biomolecule-based, target-specific, radiopharmaceuticals for SPECT imaging applications. The Institute’s strategy for this program involves interdisciplinary tasks:

Design and synthesis of functional biomolecules - Design and synthesis of the chelators for radiometal binding – Biochemical/biophysical studies of the compounds - Radiolabeling of the biomolecule-based compounds (mainly peptide derivatives, but and also antibodies/antibody fragments or small organic molecules) – Biological evaluation / Pharmacological studies on cell lines – Animal studies – Phase I clinical trials carried out in humans in collaborating hospitals. The studies are co-funded by public agencies in Greece, by NCSR “Demokritos” and also by interested industries founding joint ventures with the Institute and holding private agreements with individual researchers for the exploitation of the research products.